AI-NATIVE DRUG DISCOVERY

Finding the drivers of age-related disease, not just the signals.

Finding the drivers of age-related disease, not just the signals.

ScriptBio AI combines human single-cell data, biological foundation models, and causal inference to identify and prioritize potential therapeutic targets for age-related disease using layered causal evidence.

ScriptBio AI combines human single-cell data, biological foundation models, and causal inference to identify and prioritize potential therapeutic targets for age-related disease using layered causal evidence.

Drug discovery still starts too often with correlation.

Drug discovery still starts too often with correlation.

Disease datasets contain thousands of biological changes, but many are downstream effects rather than actionable causes. ScriptBio AI is building a target-discovery platform designed to distinguish potential disease drivers from the signals that accompany them.

Disease datasets contain thousands of biological changes, but many are downstream effects rather than actionable causes. ScriptBio AI is building a target-discovery platform designed to distinguish potential disease drivers from the signals that accompany them.

500,000+

human single-cell profiles

Five

human studies

Working

platform prototype

Initial program

knee osteoarthritis

THE PLATFORM

From human data to prioritized targets for age-related disease.

From human data to prioritized targets for age-related disease.

DATA FOUNDATION

Human data at scale

We integrate large-scale human single-cell transcriptomic data to map disease-relevant cell states across studies and patient populations.

500,000+ human single-cell profiles harmonized and analyzed across five studies.

CAUSAL DISCOVERY

Causal target discovery

Biological foundation models, multi-layer causal inference, and perturbation modeling help identify and rank targets that may influence disease state, rather than merely correlate with it.

Targets are assessed through layered causal evidence.

DECISION SUPPORT

Evidence synthesis

Agentic research workflows organize evidence from scientific literature, clinical development, intellectual property, and competitive activity to support transparent target assessment and experimental prioritization.

Structured evidence for clearer experimental decisions.

INITIAL VALIDATION PROGRAM

Starting with knee osteoarthritis.

Knee osteoarthritis provides a focused test case for evaluating whether computationally nominated targets produce reproducible, disease-relevant effects in human cells. The objective is to generate biological evidence for the platform while addressing a condition with substantial unmet need.

01

Focused proof case

Built for discovery partnerships.

Built for discovery partnerships.

ScriptBio AI is developing a flexible platform model designed to support target-discovery collaborations with pharmaceutical and biotechnology companies, while preserving the option to advance selected high-confidence programs internally.

Discuss a partnership

Let’s find better starting points for drug discovery.

Let’s find better starting points for drug discovery.

We welcome conversations with pharmaceutical and biotechnology partners, translational researchers, and investors interested in causal target discovery.

We welcome conversations with pharmaceutical and biotechnology partners, translational researchers, and investors interested in causal target discovery.

© 2026 AI Script Bio Incorporated. All rights reserved.